For patients with inflammatory skin conditions, phototherapy with ultraviolet (UV) A1 radiation induces a reduction in serum 25-hydroxyvitamin D3 (25[OH]D) levels, whereas narrowband UVB (UVBnb) and UVA/UVBnb induces significant increases in serum 25(OH)D, according to a study published in the October issue of the Journal of the American Academy of Dermatology.
(HealthDay)—For patients with inflammatory skin conditions, phototherapy with ultraviolet (UV) A1 radiation induces a reduction in serum 25-hydroxyvitamin D3 (25[OH]D) levels, whereas narrowband UVB (UVBnb) and UVA/UVBnb induces significant increases in serum 25(OH)D, according to a study published in the October issue of the Journal of the American Academy of Dermatology.
Laurence Feldmeyer, M.D., Ph.D., from University Hospital Zurich, and colleagues examined the influence of UVA1, UVBnb, and UVA/UVBnb phototherapy on serum levels of 25(OH)D and related parameters in 116 patients with atopic dermatitis, psoriasis, morphea, and other inflammatory skin conditions. The participants underwent UVA1 (38 participants), UVA/UVBnb (30 participants), or UVBnb (48 participants) two to three times per week for 53 to 90 days.
The researchers found that, after the therapy, UVBnb phototherapy correlated with a significant increase in serum 25(OH)D, from 22.1 to 39.5 ng/mL. Upon application of UVBnb phototherapy, the increase in 25(OH)D was steeper with a lower baseline 25(OH)D. A significant increase in serum 25(OH)D was also seen with UVA/UVBnb therapy, from 23.9 to 50.3 ng/mL. In contrast, in the UVA1 therapy group there was a significant decrease in 25(OH)D serum levels, from 21.9 to 19.0 ng/mL.
"In conclusion, phototherapy has an impact on 25(OH)D levels in the serum," the authors write. "Our study data [call] for closer examination of a potential confounding effect of various skin diseases and the need for oral vitamin D supplementation in UVA1-treated patients."
The study was funded by Spirig Pharmaceuticals.
Explore further: Vitamin D deficiency linked to Type 1 diabetes
More information: Abstract
Full Text (subscription or payment may be required)
Copyright © 2013 HealthDay. All rights reserved.
Medical Xpress on facebook
Related Stories
Vitamin D deficiency linked to Type 1 diabetes
Nov 15, 2012
A study led by researchers from the University of California, San Diego School of Medicine has found a correlation between vitamin D3 serum levels and subsequent incidence of Type 1 diabetes. The six-year study of blood levels ...
Sunscreen use may lead to vitamin D deficiency
Apr 27, 2012
(HealthDay) -- Using the amount and sun protection factor (SPF) of sunscreen recommended by the World Health Organization (WHO) is associated with little or no vitamin D production, suggesting that regular ...
Vitamin D supplementation does not reduce rate or severity of colds, study finds
Oct 02, 2012
Although some data have suggested a possible inverse association between serum vitamin D levels and the incidence of upper respiratory tract infections (colds), participants in a randomized controlled trial who received a ...
UV-B treatment may improve psoriasis and vitamin D levels
Aug 16, 2010
Treatment with narrow-band UV-B rays may increase serum levels of vitamin D in the wintertime while clearing psoriasis, according to a report in the August issue of Archives of Dermatology, one of the JAMA/Archives journa ...
Vitamin D2 is as effective as vitamin D3 in maintaining concentrations of 25-hydroxyvitamin D
Jan 02, 2008
Researchers from Boston University School of Medicine (BUSM) have found that vitamin D2 is equally as effective as vitamin D3 in maintaining 25-hydroxyvitamin D status. The study appears online in the December 2007 issue ...
Recommended for you
How lethal bird flu viruses evolved
1 hour ago
Deadly H7N9 avian flu viruses infected people for the first time earlier this year in China, but little is known about how they evolved to become harmful to humans. In a study published by Cell Press on September 19 in Cell Ho ...
More and more Danes infected with MRSA bacteria
3 hours ago
In 2012, 1,556 Danes were found positive with methicillin-resistant staphylococci - MRSA. This represents an increase of 20% from 2011. In fact, the total number of cases has almost doubled since 2009. MRSA ...
Bracing is effective in adolescents with idiopathic scoliosis
7 hours ago
A multi-center study led by University of Iowa researchers to determine whether wearing back braces would prevent the need for spinal correction surgery in children with adolescent idiopathic scoliosis (AIS) was cut short ...
Dengue emergency declared in Pakistan's Swat (Update)
8 hours ago
Authorities in Pakistan's northwestern Swat Valley have declared a health emergency after nearly 5,000 cases of dengue fever were reported in a month.
E-readers more effective than paper for dyslexic readers
20 hours ago
As e-readers grow in popularity as convenient alternatives to traditional books, researchers at the Smithsonian have found that convenience may not be their only benefit. The team discovered that when e-readers ...
Smartphone app found to be valid tool in screening for minimal hepatic encephalopathy
Sep 18, 2013
A smartphone app can quickly screen for cognitive dysfunction often found in patients with cirrhosis, according to a new Virginia Commonwealth University study. The cognitive dysfunction, known as minimal hepatic encephalopathy ...
User comments
© Medical Xpress 2011-2013, Phys.org network
For patients with inflammatory skin conditions, phototherapy with ultraviolet (UV) A1 radiation induces a reduction in serum 25-hydroxyvitamin D3 (25[OH]D) levels, whereas narrowband UVB (UVBnb) and UVA/UVBnb induces significant increases in serum 25(OH)D, according to a study published in the October issue of the Journal of the American Academy of Dermatology.
(HealthDay)—For patients with inflammatory skin conditions, phototherapy with ultraviolet (UV) A1 radiation induces a reduction in serum 25-hydroxyvitamin D3 (25[OH]D) levels, whereas narrowband UVB (UVBnb) and UVA/UVBnb induces significant increases in serum 25(OH)D, according to a study published in the October issue of the Journal of the American Academy of Dermatology.
Laurence Feldmeyer, M.D., Ph.D., from University Hospital Zurich, and colleagues examined the influence of UVA1, UVBnb, and UVA/UVBnb phototherapy on serum levels of 25(OH)D and related parameters in 116 patients with atopic dermatitis, psoriasis, morphea, and other inflammatory skin conditions. The participants underwent UVA1 (38 participants), UVA/UVBnb (30 participants), or UVBnb (48 participants) two to three times per week for 53 to 90 days.
The researchers found that, after the therapy, UVBnb phototherapy correlated with a significant increase in serum 25(OH)D, from 22.1 to 39.5 ng/mL. Upon application of UVBnb phototherapy, the increase in 25(OH)D was steeper with a lower baseline 25(OH)D. A significant increase in serum 25(OH)D was also seen with UVA/UVBnb therapy, from 23.9 to 50.3 ng/mL. In contrast, in the UVA1 therapy group there was a significant decrease in 25(OH)D serum levels, from 21.9 to 19.0 ng/mL.
"In conclusion, phototherapy has an impact on 25(OH)D levels in the serum," the authors write. "Our study data [call] for closer examination of a potential confounding effect of various skin diseases and the need for oral vitamin D supplementation in UVA1-treated patients."
The study was funded by Spirig Pharmaceuticals.
Explore further: Vitamin D deficiency linked to Type 1 diabetes
More information: Abstract
Full Text (subscription or payment may be required)
Copyright © 2013 HealthDay. All rights reserved.
Medical Xpress on facebook
Related Stories
Vitamin D deficiency linked to Type 1 diabetes
Nov 15, 2012
A study led by researchers from the University of California, San Diego School of Medicine has found a correlation between vitamin D3 serum levels and subsequent incidence of Type 1 diabetes. The six-year study of blood levels ...
Sunscreen use may lead to vitamin D deficiency
Apr 27, 2012
(HealthDay) -- Using the amount and sun protection factor (SPF) of sunscreen recommended by the World Health Organization (WHO) is associated with little or no vitamin D production, suggesting that regular ...
Vitamin D supplementation does not reduce rate or severity of colds, study finds
Oct 02, 2012
Although some data have suggested a possible inverse association between serum vitamin D levels and the incidence of upper respiratory tract infections (colds), participants in a randomized controlled trial who received a ...
UV-B treatment may improve psoriasis and vitamin D levels
Aug 16, 2010
Treatment with narrow-band UV-B rays may increase serum levels of vitamin D in the wintertime while clearing psoriasis, according to a report in the August issue of Archives of Dermatology, one of the JAMA/Archives journa ...
Vitamin D2 is as effective as vitamin D3 in maintaining concentrations of 25-hydroxyvitamin D
Jan 02, 2008
Researchers from Boston University School of Medicine (BUSM) have found that vitamin D2 is equally as effective as vitamin D3 in maintaining 25-hydroxyvitamin D status. The study appears online in the December 2007 issue ...
Recommended for you
How lethal bird flu viruses evolved
1 hour ago
Deadly H7N9 avian flu viruses infected people for the first time earlier this year in China, but little is known about how they evolved to become harmful to humans. In a study published by Cell Press on September 19 in Cell Ho ...
More and more Danes infected with MRSA bacteria
3 hours ago
In 2012, 1,556 Danes were found positive with methicillin-resistant staphylococci - MRSA. This represents an increase of 20% from 2011. In fact, the total number of cases has almost doubled since 2009. MRSA ...
Bracing is effective in adolescents with idiopathic scoliosis
7 hours ago
A multi-center study led by University of Iowa researchers to determine whether wearing back braces would prevent the need for spinal correction surgery in children with adolescent idiopathic scoliosis (AIS) was cut short ...
Dengue emergency declared in Pakistan's Swat (Update)
8 hours ago
Authorities in Pakistan's northwestern Swat Valley have declared a health emergency after nearly 5,000 cases of dengue fever were reported in a month.
E-readers more effective than paper for dyslexic readers
20 hours ago
As e-readers grow in popularity as convenient alternatives to traditional books, researchers at the Smithsonian have found that convenience may not be their only benefit. The team discovered that when e-readers ...
Smartphone app found to be valid tool in screening for minimal hepatic encephalopathy
Sep 18, 2013
A smartphone app can quickly screen for cognitive dysfunction often found in patients with cirrhosis, according to a new Virginia Commonwealth University study. The cognitive dysfunction, known as minimal hepatic encephalopathy ...
User comments
© Medical Xpress 2011-2013, Phys.org network
0 comments:
Post a Comment