(HealthDay)—Recent guidelines on chronic pain management agree on several opioid risk mitigation strategies, according to a review published online Nov. 12 in the Annals of Internal Medicine.
Teryl K. Nuckols, M.D., M.S.H.S., from the University of California in Los Angeles, and colleagues evaluated 13 guidelines published between January 2007 and July 2013 that address use of opioids for chronic pain management in adults. Guidelines addressing specific settings, populations, and conditions were excluded.
The researchers found that although the guidelines differed greatly in quality, most guidelines recommended that clinicians avoid doses greater than 90 to 200 mg of morphine equivalents per day; have additional knowledge to prescribe methadone; recognize risks of fentanyl patches; titrate cautiously; reduce doses by 25 to 50 percent when switching opioids; and mitigate risks by using risk assessment tools, treatment agreements, and urine drug testing.
"Future research should directly examine the effectiveness of opioid risk mitigation strategies," the authors write.
Explore further: Following bariatric surgery, use of opioids increases among chronic opioid users
More information: Full Text (subscription or payment may be required)
Copyright © 2013 HealthDay. All rights reserved.
Medical Xpress on facebook
Related Stories
Following bariatric surgery, use of opioids increases among chronic opioid users
Oct 01, 2013
In a group of patients who took chronic opioids for noncancer pain and who underwent bariatric surgery, there was greater chronic use of opioids after surgery compared with before, findings that suggest the need for proactive ...
Long-term use of prescription-based painkillers increases the risk of depression, researcher finds
Oct 31, 2013
Opioid analgesics, or prescription-based narcotic pain killers, have long been known to reduce pain, but reports of adverse effects and addiction continue to surface. Now, a team of investigators led by a Saint Louis University ...
Even small doses of opioids increase risk of road crashes, research finds
Jan 15, 2013
Drivers who have taken even a small dose of opioid painkillers have an increased risk of being injured in a car accident, a new study has found.
Health care workers trained on Rx drug abuse
Nov 07, 2013
(Medical Xpress)—A Colorado health care training course designed to curb prescription drug abuse, reports preliminary data that state-wide chronic pain prescription practices are changing since first offering the training ...
New study reveals racial disparities in chronic pain management
Feb 13, 2013
Opioids are frequently prescribed for pain management in noncancer patients, but recommended clinical guidelines for monitoring effectiveness and signs of drug abuse are often not implemented. Alongside well-documented racial ...
Recommended for you
Chronic pain and emotional distress often treated with risky medications
4 hours ago
People suffering from chronic non-cancer pain and severe emotional distress, such as depression, anxiety and substance use, are likely to receive long-term opioid therapy despite a lack of evidence that this ...
GlaxoSmithKline drug fails in late-stage study (Update)
Nov 12, 2013
A potential GlaxoSmithKline heart disease treatment acquired in a key company takeover fell short in a big, late-stage study.
Aptiom approved to treat seizures
Nov 11, 2013
(HealthDay)—Aptiom (eslicarbazepine acetate) has been approved by the U.S. Food and Drug Administration as an add-on drug to help treat adults with partial epileptic seizures.
Novartis sells blood transfusion test unit for $1.7 bn
Nov 11, 2013
Swiss pharmaceuticals giant Novartis said Monday it would sell its blood transfusion diagnostics unit to the Spanish firm Grifols for $1.68 billion (1.25 billion euros), with analysts saying more divestments could lay in ...
Shire buys ViroPharma in $4.2 billion deal (Update)
Nov 11, 2013
The drugmaker Shire PLC plans to strengthen its rare disease treatment portfolio by spending $4.2 billion in cash to buy the biopharmaceutical company ViroPharma Inc.
Generic aciphex approved to treat chronic heartburn
Nov 08, 2013
(HealthDay)—The first generic versions of the anti-GERD drug Aciphex (rabeprazole sodium) have been approved by the U.S. Food and Drug Administration for people aged 12 and older, the agency said Friday.
User comments
© Medical Xpress 2011-2013, Phys.org network
(HealthDay)—Recent guidelines on chronic pain management agree on several opioid risk mitigation strategies, according to a review published online Nov. 12 in the Annals of Internal Medicine.
Teryl K. Nuckols, M.D., M.S.H.S., from the University of California in Los Angeles, and colleagues evaluated 13 guidelines published between January 2007 and July 2013 that address use of opioids for chronic pain management in adults. Guidelines addressing specific settings, populations, and conditions were excluded.
The researchers found that although the guidelines differed greatly in quality, most guidelines recommended that clinicians avoid doses greater than 90 to 200 mg of morphine equivalents per day; have additional knowledge to prescribe methadone; recognize risks of fentanyl patches; titrate cautiously; reduce doses by 25 to 50 percent when switching opioids; and mitigate risks by using risk assessment tools, treatment agreements, and urine drug testing.
"Future research should directly examine the effectiveness of opioid risk mitigation strategies," the authors write.
Explore further: Following bariatric surgery, use of opioids increases among chronic opioid users
More information: Full Text (subscription or payment may be required)
Copyright © 2013 HealthDay. All rights reserved.
Medical Xpress on facebook
Related Stories
Following bariatric surgery, use of opioids increases among chronic opioid users
Oct 01, 2013
In a group of patients who took chronic opioids for noncancer pain and who underwent bariatric surgery, there was greater chronic use of opioids after surgery compared with before, findings that suggest the need for proactive ...
Long-term use of prescription-based painkillers increases the risk of depression, researcher finds
Oct 31, 2013
Opioid analgesics, or prescription-based narcotic pain killers, have long been known to reduce pain, but reports of adverse effects and addiction continue to surface. Now, a team of investigators led by a Saint Louis University ...
Even small doses of opioids increase risk of road crashes, research finds
Jan 15, 2013
Drivers who have taken even a small dose of opioid painkillers have an increased risk of being injured in a car accident, a new study has found.
Health care workers trained on Rx drug abuse
Nov 07, 2013
(Medical Xpress)—A Colorado health care training course designed to curb prescription drug abuse, reports preliminary data that state-wide chronic pain prescription practices are changing since first offering the training ...
New study reveals racial disparities in chronic pain management
Feb 13, 2013
Opioids are frequently prescribed for pain management in noncancer patients, but recommended clinical guidelines for monitoring effectiveness and signs of drug abuse are often not implemented. Alongside well-documented racial ...
Recommended for you
Chronic pain and emotional distress often treated with risky medications
4 hours ago
People suffering from chronic non-cancer pain and severe emotional distress, such as depression, anxiety and substance use, are likely to receive long-term opioid therapy despite a lack of evidence that this ...
GlaxoSmithKline drug fails in late-stage study (Update)
Nov 12, 2013
A potential GlaxoSmithKline heart disease treatment acquired in a key company takeover fell short in a big, late-stage study.
Aptiom approved to treat seizures
Nov 11, 2013
(HealthDay)—Aptiom (eslicarbazepine acetate) has been approved by the U.S. Food and Drug Administration as an add-on drug to help treat adults with partial epileptic seizures.
Novartis sells blood transfusion test unit for $1.7 bn
Nov 11, 2013
Swiss pharmaceuticals giant Novartis said Monday it would sell its blood transfusion diagnostics unit to the Spanish firm Grifols for $1.68 billion (1.25 billion euros), with analysts saying more divestments could lay in ...
Shire buys ViroPharma in $4.2 billion deal (Update)
Nov 11, 2013
The drugmaker Shire PLC plans to strengthen its rare disease treatment portfolio by spending $4.2 billion in cash to buy the biopharmaceutical company ViroPharma Inc.
Generic aciphex approved to treat chronic heartburn
Nov 08, 2013
(HealthDay)—The first generic versions of the anti-GERD drug Aciphex (rabeprazole sodium) have been approved by the U.S. Food and Drug Administration for people aged 12 and older, the agency said Friday.
User comments
© Medical Xpress 2011-2013, Phys.org network
0 comments:
Post a Comment