Medical undergraduate Charles Baker has developed a mathematical model to improve liver imaging methods. Inset: An image of a liver with five lesions.
A medical student from The University of Queensland has applied his background in mathematics to the field of nuclear medicine to improve liver imaging methods, which may improve diagnosis time and possibly save patients undergoing unnecessary surgery.
Third year medical undergraduate Charles Baker has developed a mathematical model that can be programmed into existing scanning equipment to enhance images of patients' livers.
Mr Baker said the model uses variables specifically relating to the structure of the liver to help nuclear medicine specialists better differentiate between healthy and damaged liver tissue.
"This means we can improve the output of existing scanning equipment to provide better image quality for nuclear medicine specialists," Mr Baker said.
"The resulting images demonstrate higher contrast between healthy liver tissue and unhealthy liver tissue, such as malignant tumours."
The mathematical model is undergoing clinical appraisal in the Nuclear Medicine Department at the Royal Brisbane and Women's Hospital (RBWH) and Mr Baker said initial feedback had been encouraging.
"We hope that practical testing of the model across a larger number of images will help identify how it will improve clinical decision-making and patient outcomes."
"For example, scans using the mathematical model may help to more clearly identify areas of dead tumour tissue and active tumour tissue. Clinicians can use this information to better target treatments."
The improved contrast would also help specialists to more easily interpret scans, saving time.
"Most importantly, the higher contrast scans might save people from undergoing unnecessary surgical procedures," Mr Baker said.
He is now working on mathematical models to improve imaging in other parts of the body, such as the brain.
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Medical undergraduate Charles Baker has developed a mathematical model to improve liver imaging methods. Inset: An image of a liver with five lesions.
A medical student from The University of Queensland has applied his background in mathematics to the field of nuclear medicine to improve liver imaging methods, which may improve diagnosis time and possibly save patients undergoing unnecessary surgery.
Third year medical undergraduate Charles Baker has developed a mathematical model that can be programmed into existing scanning equipment to enhance images of patients' livers.
Mr Baker said the model uses variables specifically relating to the structure of the liver to help nuclear medicine specialists better differentiate between healthy and damaged liver tissue.
"This means we can improve the output of existing scanning equipment to provide better image quality for nuclear medicine specialists," Mr Baker said.
"The resulting images demonstrate higher contrast between healthy liver tissue and unhealthy liver tissue, such as malignant tumours."
The mathematical model is undergoing clinical appraisal in the Nuclear Medicine Department at the Royal Brisbane and Women's Hospital (RBWH) and Mr Baker said initial feedback had been encouraging.
"We hope that practical testing of the model across a larger number of images will help identify how it will improve clinical decision-making and patient outcomes."
"For example, scans using the mathematical model may help to more clearly identify areas of dead tumour tissue and active tumour tissue. Clinicians can use this information to better target treatments."
The improved contrast would also help specialists to more easily interpret scans, saving time.
"Most importantly, the higher contrast scans might save people from undergoing unnecessary surgical procedures," Mr Baker said.
He is now working on mathematical models to improve imaging in other parts of the body, such as the brain.
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Medical Xpress on facebook
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Oct 29, 2013
Bowel cancer patients whose disease has spread to the liver are not being referred to specialists for potentially life-saving surgery, according to research published in the British Journal of Surgery.
3-D MRI scans may offer better way to predict survival after chemo for liver tumors
Mar 26, 2014
In a series of studies involving 140 American men and women with liver tumors, researchers at Johns Hopkins have used specialized 3-D MRI scans to precisely measure living and dying tumor tissue to quickly show whether highly ...
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Apr 15, 2014
Over 20 years after the fatal fialuridine trial, a study published this week in PLOS Medicine demonstrates that mice with humanized livers recapitulate the drug's toxicity. The work suggests that this mouse model should be add ...
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Mar 12, 2012
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17 hours ago
A new study in Nature challenges research data that form the scientific basis of clinical trials in which heart attack patients are injected with stem cells to try and regenerate damaged heart tissue.
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21 hours ago
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