Monday, 23 March 2015

High-definition scans suggest effects of smoking may be seen in unborn babies






4-D scans show a sequence of movements displayed by two fetuses at 32 weeks gestation. The image shows fetal movements in a fetus whose mother is a smoker (top) and a fetus whose mother is a non-smoker (below). Credit: Dr. Nadja Reissland, Durham University

The harmful effects of smoking during pregnancy may be reflected in the facial movements of mothers' unborn babies, new research has suggested.



Researchers at Durham and Lancaster universities said the findings of their added weight to existing evidence that smoking is harmful to as they develop in the womb and warranted further investigation.


Observing 4-d ultrasound scans, the researchers found that fetuses whose mothers were smokers showed a significantly higher rate of than the normal declining rate of movements expected in a fetus during pregnancy.


The researchers suggested that the reason for this might be that the fetal central nervous system, which controls movements in general and in particular did not develop at the same rate and in the same manner as in fetuses of mothers who did not smoke during pregnancy.


Previous studies have reported a delay in relation to speech processing abilities in infants exposed to , the researchers added.


The researchers observed 80 4-d ultrasound scans of 20 fetuses, to assess subtle mouth and touch movements. Scans were taken at four different intervals between 24 and 36 weeks of pregnancy.


Four of the fetuses belonged to mothers who smoked an average of 14 cigarettes per day, while the remaining 16 fetuses were being carried by mothers who were non-smokers. All fetuses were clinically assessed and were healthy when born.


In common with other studies, the research also showed that maternal stress and depression have a significant impact on fetal movements, but that the increase in mouth and touch movements was even higher in babies whose mothers smoked.


The study also found some evidence of a bigger delay in the reduction of facial touching by fetuses whose mothers smoked, compared to the fetuses of non-smokers, but the researchers said this delay was less significant.


The research is published in the journal Acta Paediatrica.


Lead author Dr Nadja Reissland, in Durham University's Department of Psychology, said: "Fetal facial movement patterns differ significantly between fetuses of mothers who smoked compared to those of who didn't smoke.


"Our findings concur with others that stress and depression have a significant impact on , and need to be controlled for, but additionally these results point to the fact that nicotine exposure per se has an effect on fetal development over and above the effects of stress and depression.


"A larger study is needed to confirm these results and to investigate specific effects, including the interaction of and smoking."


Co-author Professor Brian Francis, of Lancaster University, added: "Technology means we can now see what was previously hidden, revealing how smoking affects the development of the fetus in ways we did not realise. This is yet further evidence of the negative effects of smoking in pregnancy."


The researchers stressed that their research was a pilot study and that larger studies were needed to confirm and further understand the relationship between maternal smoking, stress, depression and .


They added that future studies should also take into account the smoking behaviours of fathers.



More information: Acta Paediatrica, http://ift.tt/1q9dxEm 1/apa.13001/abstract


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4-D scans show a sequence of movements displayed by two fetuses at 32 weeks gestation. The image shows fetal movements in a fetus whose mother is a smoker (top) and a fetus whose mother is a non-smoker (below). Credit: Dr. Nadja Reissland, Durham University


The harmful effects of smoking during pregnancy may be reflected in the facial movements of mothers' unborn babies, new research has suggested.



Researchers at Durham and Lancaster universities said the findings of their added weight to existing evidence that smoking is harmful to as they develop in the womb and warranted further investigation.


Observing 4-d ultrasound scans, the researchers found that fetuses whose mothers were smokers showed a significantly higher rate of than the normal declining rate of movements expected in a fetus during pregnancy.


The researchers suggested that the reason for this might be that the fetal central nervous system, which controls movements in general and in particular did not develop at the same rate and in the same manner as in fetuses of mothers who did not smoke during pregnancy.


Previous studies have reported a delay in relation to speech processing abilities in infants exposed to , the researchers added.


The researchers observed 80 4-d ultrasound scans of 20 fetuses, to assess subtle mouth and touch movements. Scans were taken at four different intervals between 24 and 36 weeks of pregnancy.


Four of the fetuses belonged to mothers who smoked an average of 14 cigarettes per day, while the remaining 16 fetuses were being carried by mothers who were non-smokers. All fetuses were clinically assessed and were healthy when born.


In common with other studies, the research also showed that maternal stress and depression have a significant impact on fetal movements, but that the increase in mouth and touch movements was even higher in babies whose mothers smoked.


The study also found some evidence of a bigger delay in the reduction of facial touching by fetuses whose mothers smoked, compared to the fetuses of non-smokers, but the researchers said this delay was less significant.


The research is published in the journal Acta Paediatrica.


Lead author Dr Nadja Reissland, in Durham University's Department of Psychology, said: "Fetal facial movement patterns differ significantly between fetuses of mothers who smoked compared to those of who didn't smoke.


"Our findings concur with others that stress and depression have a significant impact on , and need to be controlled for, but additionally these results point to the fact that nicotine exposure per se has an effect on fetal development over and above the effects of stress and depression.


"A larger study is needed to confirm these results and to investigate specific effects, including the interaction of and smoking."


Co-author Professor Brian Francis, of Lancaster University, added: "Technology means we can now see what was previously hidden, revealing how smoking affects the development of the fetus in ways we did not realise. This is yet further evidence of the negative effects of smoking in pregnancy."


The researchers stressed that their research was a pilot study and that larger studies were needed to confirm and further understand the relationship between maternal smoking, stress, depression and .


They added that future studies should also take into account the smoking behaviours of fathers.



More information: Acta Paediatrica, http://ift.tt/1q9dxEm 1/apa.13001/abstract


Medical Xpress on facebook


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Left-handed fetuses could show effects of maternal stress on unborn babies


Jun 02, 2014

Fetuses are more likely to show left-handed movements in the womb when their mothers are stressed, according to new research.



Unborn babies 'practise' facial expressions in the womb


Jun 07, 2013

(Medical Xpress)—Unborn babies 'practise' facial expressions of pain in the womb, according to a study published today.



Babies learn to anticipate touch in the womb


Oct 07, 2013

Babies learn how to anticipate touch while in the womb, according to new research by Durham and Lancaster universities.



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