If a lump is found in the breast of an adolescent girl, she often will undergo an excisional biopsy. However, breast cancer is rare in adolescents, and the vast majority of teenage breast lumps turn out to be benign masses that are related to hormones and often go away over time.
A recent Loyola University Health System study published in the Journal of Ultrasound in Medicine suggests that a breast ultrasound examination might eliminate the need for biopsy in many cases.
Loyola radiologists studied 37 teen girls with a total of 45 breast lumps to determine whether the size of their breast mass at an initial ultrasound and their growth at a follow-up ultrasound could be used to decide between conservative management of the lump or a more invasive tissue biopsy.
The girls were divided into three groups. The breast masses in group one (n = 9) underwent a follow-up ultrasound and a biopsy. Group two (n = 13) masses only had a biopsy and group three (n = 23) masses underwent a follow-up ultrasound with no biopsy. None of the lumps showed changes in appearance at the follow-up ultrasound, and all biopsied lumps were benign.
Other factors were studied, including lump dimension, volume and volume change. The researchers concluded that if only those breast masses with a largest dimension greater than 3 cm and a volume change per month greater than 16 percent had undergone biopsies then the biopsies could have been reduced in 89 percent of girls in group one and 96 percent in group three of their patients.
"These findings suggest that if at a follow-up breast ultrasound, if a benign appearing breast mass does not meet the combined criteria of largest dimension greater than 3 cm and volume change per month greater than 16 percent then it need not undergo biopsy," said lead author Aruna Vade, MD, a professor in the Department of Radiology at Loyola University Chicago Stritch School of Medicine.
In an excisional biopsy, the surgeon makes an incision along the contour of the breast and removes the lump. However, this procedure can result in pain, scarring and breast deformity.
Vade and her colleagues recommend that excisional biopsies be reserved for solid breast masses that are sonographically suspicious for malignancy or breast masses or show progressive growth or are found in patients who have a known primary malignant tumor or family history of cancer
Explore further: New breast cancer risk prediction model more accurate current model
Medical Xpress on facebook
Related Stories
What should a teenage girl do if she finds a lump in her breast?
If a lump is found in the breast of an adolescent girl, she often will undergo an excisional biopsy.
3-D doppler ultrasound helps identify breast cancer
Three-dimensional (3-D) power Doppler ultrasound helps radiologists distinguish between malignant and benign breast masses, according to a new study being published in the November issue of Radiology.
Ultrasound proves safe alternative to biopsy in some breast masses
Researchers have reported that breast masses shown on ultrasound that are diagnosed as “probably benign” can be safely managed with imaging follow-up rather than biopsy, according to a study appearing in the July issue ...
Multiple bilateral circumscribed breast masses usually benign
(HealthDay)—Multiple bilateral (MB) circumscribed breast masses detected with ultrasound screening are almost always benign, according to research published in the September issue of Radiology.
Elastography helps identify patients who need biopsy
A new ultrasound technique is proving valuable in distinguishing malignant from benign breast lesions in some patients – results that could mean fewer unnecessary breast biopsies, a new study shows.
Recommended for you
Fasting and less-toxic cancer drug may work as well as chemotherapy
Fasting in combination with chemotherapy has already been shown to kill cancer cells, but a pair of new studies in mice suggests that a less-toxic class of drugs combined with fasting may kill breast, colorectal ...
Low vitamin D linked to worse prognosis in type of non-Hodgkin lymphoma
A new study found that people with lower vitamin D levels prior to treatment for follicular lymphoma succumb to the disease or face relapse earlier than patients with sufficient vitamin D levels in their blood.
Panel predicts whether rare leukemia will respond to treatment
Patients with chronic myelomonocytic leukemia have limited treatment options, and those that exist are effective only in fewer than half of patients. Now, a new study identifies a panel of genetic markers ...
New drug stalls estrogen receptor-positive cancer cell growth and shrinks tumors
An experimental drug rapidly shrinks most tumors in a mouse model of human breast cancer, researchers report in the Proceedings of the National Academy of Sciences. When mice were treated with the experi ...
To stop cancer: Block its messages
The average living cell needs communication skills: It must transmit a constant stream of messages quickly and efficiently from its outer walls to the inner nucleus, where most of the day-to-day decisions ...
Team identifies new gene involved in hereditary neuroendocrine tumors
Researchers in the Hereditary Endocrine Cancer Group of the Spanish National Cancer Research Centre (CNIO)—led by Alberto Cascón and Mercedes Robledo—have described the presence of mutations in the MDH2 ...
User comments
Please sign in to add a comment. Registration is free, and takes less than a minute. Read more
Click here to reset your password.
Sign in to get notified via email when new comments are made.
If a lump is found in the breast of an adolescent girl, she often will undergo an excisional biopsy. However, breast cancer is rare in adolescents, and the vast majority of teenage breast lumps turn out to be benign masses that are related to hormones and often go away over time.
A recent Loyola University Health System study published in the Journal of Ultrasound in Medicine suggests that a breast ultrasound examination might eliminate the need for biopsy in many cases.
Loyola radiologists studied 37 teen girls with a total of 45 breast lumps to determine whether the size of their breast mass at an initial ultrasound and their growth at a follow-up ultrasound could be used to decide between conservative management of the lump or a more invasive tissue biopsy.
The girls were divided into three groups. The breast masses in group one (n = 9) underwent a follow-up ultrasound and a biopsy. Group two (n = 13) masses only had a biopsy and group three (n = 23) masses underwent a follow-up ultrasound with no biopsy. None of the lumps showed changes in appearance at the follow-up ultrasound, and all biopsied lumps were benign.
Other factors were studied, including lump dimension, volume and volume change. The researchers concluded that if only those breast masses with a largest dimension greater than 3 cm and a volume change per month greater than 16 percent had undergone biopsies then the biopsies could have been reduced in 89 percent of girls in group one and 96 percent in group three of their patients.
"These findings suggest that if at a follow-up breast ultrasound, if a benign appearing breast mass does not meet the combined criteria of largest dimension greater than 3 cm and volume change per month greater than 16 percent then it need not undergo biopsy," said lead author Aruna Vade, MD, a professor in the Department of Radiology at Loyola University Chicago Stritch School of Medicine.
In an excisional biopsy, the surgeon makes an incision along the contour of the breast and removes the lump. However, this procedure can result in pain, scarring and breast deformity.
Vade and her colleagues recommend that excisional biopsies be reserved for solid breast masses that are sonographically suspicious for malignancy or breast masses or show progressive growth or are found in patients who have a known primary malignant tumor or family history of cancer
Explore further: New breast cancer risk prediction model more accurate current model
Medical Xpress on facebook
Related Stories
What should a teenage girl do if she finds a lump in her breast?
If a lump is found in the breast of an adolescent girl, she often will undergo an excisional biopsy.
3-D doppler ultrasound helps identify breast cancer
Three-dimensional (3-D) power Doppler ultrasound helps radiologists distinguish between malignant and benign breast masses, according to a new study being published in the November issue of Radiology.
Ultrasound proves safe alternative to biopsy in some breast masses
Researchers have reported that breast masses shown on ultrasound that are diagnosed as “probably benign” can be safely managed with imaging follow-up rather than biopsy, according to a study appearing in the July issue ...
Multiple bilateral circumscribed breast masses usually benign
(HealthDay)—Multiple bilateral (MB) circumscribed breast masses detected with ultrasound screening are almost always benign, according to research published in the September issue of Radiology.
Elastography helps identify patients who need biopsy
A new ultrasound technique is proving valuable in distinguishing malignant from benign breast lesions in some patients – results that could mean fewer unnecessary breast biopsies, a new study shows.
Recommended for you
Fasting and less-toxic cancer drug may work as well as chemotherapy
Fasting in combination with chemotherapy has already been shown to kill cancer cells, but a pair of new studies in mice suggests that a less-toxic class of drugs combined with fasting may kill breast, colorectal ...
Low vitamin D linked to worse prognosis in type of non-Hodgkin lymphoma
A new study found that people with lower vitamin D levels prior to treatment for follicular lymphoma succumb to the disease or face relapse earlier than patients with sufficient vitamin D levels in their blood.
Panel predicts whether rare leukemia will respond to treatment
Patients with chronic myelomonocytic leukemia have limited treatment options, and those that exist are effective only in fewer than half of patients. Now, a new study identifies a panel of genetic markers ...
New drug stalls estrogen receptor-positive cancer cell growth and shrinks tumors
An experimental drug rapidly shrinks most tumors in a mouse model of human breast cancer, researchers report in the Proceedings of the National Academy of Sciences. When mice were treated with the experi ...
To stop cancer: Block its messages
The average living cell needs communication skills: It must transmit a constant stream of messages quickly and efficiently from its outer walls to the inner nucleus, where most of the day-to-day decisions ...
Team identifies new gene involved in hereditary neuroendocrine tumors
Researchers in the Hereditary Endocrine Cancer Group of the Spanish National Cancer Research Centre (CNIO)—led by Alberto Cascón and Mercedes Robledo—have described the presence of mutations in the MDH2 ...
User comments
Please sign in to add a comment. Registration is free, and takes less than a minute. Read more
Click here
to reset your password.
Sign in to get notified via email when new comments are made.
0 comments:
Post a Comment