(HealthDay)—For patients with thyroid eye disease (TED), a contact lens sensor provides a safe and well-tolerated approach for 24-hour intraocular pressure (IOP) monitoring, according to a study published in the March issue of Clinical & Experimental Ophthalmology.
Anjali S. Parekh, M.D., from the University of California in San Diego, and colleagues conducted a prospective study in 10 patients with established TED (mean age, 61.8 years; 90 percent female) to examine the safety, tolerability, and 24-hour IOP patterns using a contact lens sensor. The authors assessed the incidence of adverse events and tolerability (scale of 0 to 10, increasing intolerance); a cosinor rhythmometry model was used to assess IOP patterns.
The researchers found that the main adverse events were blurred vision, conjunctival hyperemia, and superficial punctate keratitis (50, 100, and 20 percent, respectively). The lens tolerability was found to be 1.5 ± 0.7. Using a contact lens sensor signal, positive linear slopes were detected from wake to sleep (P = 0.254), whereas there was a significant decrease at the transition from sleep/supine to wake/sitting (P = 0.010). A significant nocturnal/sleep acrophase was seen in five patients, with the peak occurring at 6:30 a.m. The 24-hour curves had a mean amplitude of 102.2 ± 52.6 a.u.
"The contact lens sensor provides a safe and well-tolerated approach to 24-hour IOP monitoring," the authors write.
Several authors disclosed financial ties to medical device companies, including Sensimed AG, which funded the study.
Explore further: Hygiene practices affect contact lens case contamination
More information: Abstract
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(HealthDay)—For patients with thyroid eye disease (TED), a contact lens sensor provides a safe and well-tolerated approach for 24-hour intraocular pressure (IOP) monitoring, according to a study published in the March issue of Clinical & Experimental Ophthalmology.
Anjali S. Parekh, M.D., from the University of California in San Diego, and colleagues conducted a prospective study in 10 patients with established TED (mean age, 61.8 years; 90 percent female) to examine the safety, tolerability, and 24-hour IOP patterns using a contact lens sensor. The authors assessed the incidence of adverse events and tolerability (scale of 0 to 10, increasing intolerance); a cosinor rhythmometry model was used to assess IOP patterns.
The researchers found that the main adverse events were blurred vision, conjunctival hyperemia, and superficial punctate keratitis (50, 100, and 20 percent, respectively). The lens tolerability was found to be 1.5 ± 0.7. Using a contact lens sensor signal, positive linear slopes were detected from wake to sleep (P = 0.254), whereas there was a significant decrease at the transition from sleep/supine to wake/sitting (P = 0.010). A significant nocturnal/sleep acrophase was seen in five patients, with the peak occurring at 6:30 a.m. The 24-hour curves had a mean amplitude of 102.2 ± 52.6 a.u.
"The contact lens sensor provides a safe and well-tolerated approach to 24-hour IOP monitoring," the authors write.
Several authors disclosed financial ties to medical device companies, including Sensimed AG, which funded the study.
Explore further: Hygiene practices affect contact lens case contamination
More information: Abstract
Full Text (subscription or payment may be required)
Copyright © 2015 HealthDay. All rights reserved.
Medical Xpress on facebook
Related Stories
Contact lens sensor measures 24-hour intraocular pressure
(HealthDay) -- A contact lens sensor (CLS) provides safe and tolerable 24-hour monitoring of intraocular pressure (IOP) patterns in patients with or suspected of having glaucoma, according to research published ...
Hygiene practices affect contact lens case contamination
Contact lens wearers who don't follow certain hygiene habits have increased bacterial contamination of their contact lens cases, reports a study in the February issue of Optometry and Vision Science, official journal of the ...
Eye implant could lead to better glaucoma treatment
For the 2.2 million Americans battling glaucoma, the main course of action for staving off blindness involves weekly visits to eye specialists, who monitor—and control—increasing pressure within the eye.
Morning vs nighttime replacement affects adverse events with extended-wear contact lenses
For people using 30-day extended-wear/continuous-wear (EW/CW) contact lenses, replacing lenses at night doesn't lower the risk of complications compared to changing lenses monthly, suggests a study – "The Effect of Daily ...
Contacts uncomfortable? Changing lens type or lens care product may help
If your contact lenses are causing you discomfort, simply switching to a different type of contact lens or lens care product may bring improvement, reports a study, " Effect of Lens and Solution Choice on the Comfort of Contact ...
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Healing indicators after pterygium excision proposed
(HealthDay)—After pterygium excision, the sequence of tissue restoration appears to start in the cornea and end in the limbal area, according to a study published online March 31 in Ophthalmic & Physiological Op ...
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(HealthDay)—Immediately sequential bilateral cataract surgery seems beneficial, with faster rehabilitation, improved visual outcome, and savings in time and costs, according to a review published online ...
One test can predict which kids will become nearsighted
A study of 4,500 U.S. children over 20 years has identified a single test that can predict which kids will become nearsighted by the eighth grade: a measure of their current refractive error.
Allow NHS doctors to prescribe cheap, safe and effective sight loss drug, says The BMJ
NHS doctors should be allowed to prescribe a cheap, safe and effective drug for the degenerative eye disease, wet age related macular degeneration (AMD) - a leading cause of blindness among older patients, says an investigation ...
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