Friday, 10 April 2015

Tekmira will resume safety study of Ebola drug within weeks





Canadian drugmaker Tekmira Pharmaceuticals said Friday it will restart a study of an experimental Ebola treatment in the coming weeks.



The company said the Food and Drug Administration will allow it to administer the drug, called TKM-Ebola, to a small number of once a day for a one-week safety trial. Some patients in the trial will receive TKM-Ebola and the rest will get a placebo injection.


The company said it expects results from the study in the second half of 2015.


Shares of Tekmira Pharmaceuticals Corp. lost 15 cents to $17.45 in midday trading.


TKM-Ebola is designed to work by blocking genes that help the virus reproduce and spread. Tekmira started giving single doses to healthy people in 2014, but the FDA stopped the study in July because it wanted more information about the safety higher doses.


The agency allowed Tekmira to continue giving the drug to patients who were infected with the Ebola virus.


Tekmira does not have any approved drugs, and it is running early-stage studies of a treatment for the liver-damaging hepatitis B virus.



© 2015 The Associated Press. All rights reserved.


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Canadian drugmaker Tekmira Pharmaceuticals said Friday it will restart a study of an experimental Ebola treatment in the coming weeks.



The company said the Food and Drug Administration will allow it to administer the drug, called TKM-Ebola, to a small number of once a day for a one-week safety trial. Some patients in the trial will receive TKM-Ebola and the rest will get a placebo injection.


The company said it expects results from the study in the second half of 2015.


Shares of Tekmira Pharmaceuticals Corp. lost 15 cents to $17.45 in midday trading.


TKM-Ebola is designed to work by blocking genes that help the virus reproduce and spread. Tekmira started giving single doses to healthy people in 2014, but the FDA stopped the study in July because it wanted more information about the safety higher doses.


The agency allowed Tekmira to continue giving the drug to patients who were infected with the Ebola virus.


Tekmira does not have any approved drugs, and it is running early-stage studies of a treatment for the liver-damaging hepatitis B virus.



© 2015 The Associated Press. All rights reserved.


Medical Xpress on facebook


Related Stories


FDA lifts hold on experimental Ebola drug


date Aug 07, 2014

Federal health authorities have eased safety restrictions on an experimental drug to treat Ebola, a move that could clear the way for its use against an unprecedented outbreak of the deadly virus in West Africa.



New Ebola treatment trial starts in Sierra Leone


date Mar 12, 2015

A clinical trial of a potential Ebola therapy, led by Oxford University, is underway in Sierra Leone.



Scientists racing to test Ebola vaccines in humans


date Aug 14, 2014

Scientists are racing to begin the first human safety tests of two experimental Ebola vaccines, but it won't be easy to prove that the shots and other potential treatments in the pipeline really work.



Chimerix gets FDA OK to test drug for Ebola


date Oct 17, 2014

(AP)—A North Carolina drugmaker plans to test its experimental antiviral drug in patients who have Ebola, after getting authorization from regulators at the Food and Drug Administration.



Ebola drugs: A factfile


date Jan 23, 2015

There is no licensed vaccine or treatment for Ebola, which has killed more than 8,600 people in West Africa out of more than 21,700 infected since the start of 2014.





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date 3 hours ago

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date 5 hours ago

The World Health Organization says the year-long Ebola outbreak in West Africa still qualifies as an international emergency even though the number of cases has plummeted.




New TB drug offers glimmer of hope in S.Africa


date 9 hours ago

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date 11 hours ago

Days after a foodborne illness was linked to Blue Bell ice cream products, a state inspection of an Oklahoma plant later tied to the infection praised the facility for having no violations and doing a "great job," according ...




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