A new study describes a model that estimates the economic consequences of using the T2Candida Panel (a novel diagnostic product that provides Candida detection) as an adjunct to the current blood culture-based diagnostic strategy in a high-risk hospital patient cohort. It estimates that a typical hospital could save as much as $5,858,448 in total annual hospital costs. The study was published online ahead of print in Future Microbiology.
Candida species are a lethal form of common bloodstream infections that cause sepsis. They are associated with high patient mortality and excess inpatient costs because growth-based detection of Candida can delay treatment decisions. Improvements in outcomes are dependent on early identification of candidemia and timely administration of appropriate antifungal therapy. The T2Candida Panel is the first diagnostic test to provide species-specific Candida detection and identification directly from whole blood in 3 to 5 hours, without the need for blood culture.
"We are greatly encouraged by the benefits these data show for the early detection of Candida with our T2Candida Panel," said John McDonough, chief executive officer of T2 Biosystems. "The findings from this study demonstrate not only significant reduction in hospital costs, but most importantly, the potential to save so many patient lives by providing faster diagnostic results—supporting our goal of changing the paradigm in sepsis diagnosis. We look forward to working closely with the medical community to help implement this important change."
Using a decision tree model, the economic effect of using this diagnostic strategy over 1 year in a hospital setting was calculated. It also calculated Candida-related deaths per hospital could be reduced by 60.6%.
"Hospitals need to reduce the burden of bloodstream infections that cause sepsis in high risk patients, such as those with compromised immune systems. This new and interesting study estimates that that use of this diagnostic test could not only reduce hospital costs, but also reduce mortality rates," said Natasha Leeson, Commissioning Editor of Future Microbiology.
Explore further: New test could significantly reduce burden on UK hospitals
More information: The article is freely available online at http://ift.tt/1IJH1OM and will appear in an upcoming print edition of the journal.
Provided by Future Science Group
Medical Xpress on facebook
Related Stories
T2 Biosystems publishes data supporting diagnostic test T2Candida
Apr 24, 2013
T2 Biosystems, a company developing direct detection products enabling superior diagnostics, today announced the publication of research supporting the Company's flagship diagnostic test, T2Candida, in Science Translational Me ...
Researchers find quick candida test
Aug 02, 2011
A team led by a Massey University researcher has developed a diagnostic tool that could save the lives of some of the 60 people estimated to die each year in New Zealand from the fungal infection candidemia – and thousands ...
New test could significantly reduce burden on UK hospitals
Feb 20, 2015
A new test that rules out heart attacks in patients could reduce hospital admissions by as much as 40%, for patients with chest pain, according to research published by Bournemouth University (BU).
How a deadly fungus evades the immune system
Mar 31, 2015
New research from the University of Toronto has scientists re-thinking how a lethal fungus grows and kills immune cells. The study hints at a new approach to therapy for Candida albicans, one of the most c ...
Blood test for yeast infections approved
Sep 23, 2014
(HealthDay)—The first blood test to detect five strains of yeast that cause rare blood infections in people with weakened immune systems has been approved by the U.S. Food and Drug Administration.
Recommended for you
Plotting the elimination of dengue
1 minute ago
Dengue is a viral infection spread between humans by Aedes aegypti mosquitoes. Dengue causes flu-like symptoms, including intense headaches and joint pains.
Searching the microbiome for clues to managing inflammatory bowel disease
1 hour ago
Sometimes the best medicine is the most basic. Just ask any of the patients with inflammatory bowel disease who are following a new diet designed to reduce the debilitating symptoms of the illness, developed by Barbara Olendzki, ...
Talking turkey: How bird flu outbreaks are playing out
1 hour ago
A deadly strain of bird flu has reached the Midwest, killing or requiring hundreds of thousands of turkeys to be euthanized. Some questions and answers about the outbreak:
WHO sets up emergency rapid response network
1 hour ago
The World Health Organization launched a new network of rapid response medical teams Wednesday to react to humanitarian crises across the globe.
Climate change affects where vectors proliferate and also transforms pathogens
2 hours ago
Accurate forecasts of a changing climate may not be enough to predict future risk from disease transmission, as the carriers themselves are always changing. In other words, seeing into the future is complicated.
New study indicates that exercise improves non-alcoholic fatty liver disease
10 hours ago
Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease in the western world. A new study published in the Journal of Hepatology shows that exercise, regardless of fre ...
User comments
Please sign in to add a comment. Registration is free, and takes less than a minute. Read more
Click here to reset your password.
Sign in to get notified via email when new comments are made.
A new study describes a model that estimates the economic consequences of using the T2Candida Panel (a novel diagnostic product that provides Candida detection) as an adjunct to the current blood culture-based diagnostic strategy in a high-risk hospital patient cohort. It estimates that a typical hospital could save as much as $5,858,448 in total annual hospital costs. The study was published online ahead of print in Future Microbiology.
Candida species are a lethal form of common bloodstream infections that cause sepsis. They are associated with high patient mortality and excess inpatient costs because growth-based detection of Candida can delay treatment decisions. Improvements in outcomes are dependent on early identification of candidemia and timely administration of appropriate antifungal therapy. The T2Candida Panel is the first diagnostic test to provide species-specific Candida detection and identification directly from whole blood in 3 to 5 hours, without the need for blood culture.
"We are greatly encouraged by the benefits these data show for the early detection of Candida with our T2Candida Panel," said John McDonough, chief executive officer of T2 Biosystems. "The findings from this study demonstrate not only significant reduction in hospital costs, but most importantly, the potential to save so many patient lives by providing faster diagnostic results—supporting our goal of changing the paradigm in sepsis diagnosis. We look forward to working closely with the medical community to help implement this important change."
Using a decision tree model, the economic effect of using this diagnostic strategy over 1 year in a hospital setting was calculated. It also calculated Candida-related deaths per hospital could be reduced by 60.6%.
"Hospitals need to reduce the burden of bloodstream infections that cause sepsis in high risk patients, such as those with compromised immune systems. This new and interesting study estimates that that use of this diagnostic test could not only reduce hospital costs, but also reduce mortality rates," said Natasha Leeson, Commissioning Editor of Future Microbiology.
Explore further: New test could significantly reduce burden on UK hospitals
More information: The article is freely available online at http://ift.tt/1IJH1OM and will appear in an upcoming print edition of the journal.
Provided by Future Science Group
Medical Xpress on facebook
Related Stories
T2 Biosystems publishes data supporting diagnostic test T2Candida
Apr 24, 2013
T2 Biosystems, a company developing direct detection products enabling superior diagnostics, today announced the publication of research supporting the Company's flagship diagnostic test, T2Candida, in Science Translational Me ...
Researchers find quick candida test
Aug 02, 2011
A team led by a Massey University researcher has developed a diagnostic tool that could save the lives of some of the 60 people estimated to die each year in New Zealand from the fungal infection candidemia – and thousands ...
New test could significantly reduce burden on UK hospitals
Feb 20, 2015
A new test that rules out heart attacks in patients could reduce hospital admissions by as much as 40%, for patients with chest pain, according to research published by Bournemouth University (BU).
How a deadly fungus evades the immune system
Mar 31, 2015
New research from the University of Toronto has scientists re-thinking how a lethal fungus grows and kills immune cells. The study hints at a new approach to therapy for Candida albicans, one of the most c ...
Blood test for yeast infections approved
Sep 23, 2014
(HealthDay)—The first blood test to detect five strains of yeast that cause rare blood infections in people with weakened immune systems has been approved by the U.S. Food and Drug Administration.
Recommended for you
Plotting the elimination of dengue
1 minute ago
Dengue is a viral infection spread between humans by Aedes aegypti mosquitoes. Dengue causes flu-like symptoms, including intense headaches and joint pains.
Searching the microbiome for clues to managing inflammatory bowel disease
1 hour ago
Sometimes the best medicine is the most basic. Just ask any of the patients with inflammatory bowel disease who are following a new diet designed to reduce the debilitating symptoms of the illness, developed by Barbara Olendzki, ...
Talking turkey: How bird flu outbreaks are playing out
1 hour ago
A deadly strain of bird flu has reached the Midwest, killing or requiring hundreds of thousands of turkeys to be euthanized. Some questions and answers about the outbreak:
WHO sets up emergency rapid response network
1 hour ago
The World Health Organization launched a new network of rapid response medical teams Wednesday to react to humanitarian crises across the globe.
Climate change affects where vectors proliferate and also transforms pathogens
2 hours ago
Accurate forecasts of a changing climate may not be enough to predict future risk from disease transmission, as the carriers themselves are always changing. In other words, seeing into the future is complicated.
New study indicates that exercise improves non-alcoholic fatty liver disease
10 hours ago
Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease in the western world. A new study published in the Journal of Hepatology shows that exercise, regardless of fre ...
User comments
Please sign in to add a comment. Registration is free, and takes less than a minute. Read more
Click here
to reset your password.
Sign in to get notified via email when new comments are made.
0 comments:
Post a Comment